Cerebellar Ataxia, Opsoclonus, and Neuroblastoma
نویسندگان
چکیده
منابع مشابه
Neuroblastoma and opsoclonus-myoclonus-ataxia syndrome--clinical and pathological characteristics.
INTRODUCTION Opsoclonus-myoclonus-ataxia (OMA) syndrome is the most common paraneoplastic neurological syndrome in childhood. MATERIALS AND METHODS We reviewed the literature and reported on clinical and pathological characteristics of four children with OMA and peripheral neuroblastic tumours. In two of the children the onset of neurological symptoms was connected with a vaccination and in o...
متن کاملClinical Responses to Rituximab in a Case of Neuroblastoma with Refractory Opsoclonus Myoclonus Ataxia Syndrome
Opsoclonus myoclonus ataxia syndrome (OMS) is a rare neurologic syndrome. In a high proportion of children, it is associated with neuroblastoma. The etiology of this condition is thought to be immune mediated. In children, immunotherapy with conventional treatments such as corticosteroids, intravenous immunoglobulin, adrenocorticotropic hormone, and even antiepileptic drugs has been tried. Rece...
متن کاملHow Reliable are Urine Catecholamines in the Workup of Neuroblastoma Associated with Opsoclonus Myoclonus Ataxia?
We report a rare case of neuroblastoma with Opsoclonus Myoclonus Ataxia (OMA) and Horner’s syndrome in a previously healthy 17-month-old female who presented with titubations and a wide based gait. The patient had an initial negative workup including urine catecholamines. After further investigation, including a Magnetic Resonance Imaging (MRI) of the spine, neuroblastoma was revealed. This cas...
متن کاملTransient opsoclonus-myoclonus syndrome secondary to neuroblastoma.
We report a 2.5-year-old girl who presented with acute history of fluctuating level of consciousness in the form of drowsiness, extreme irritability, and involuntary abnormal movements in the form of shaking of the whole body. She was treated with acyclovir empirically, contemplating herpes simplex virus encephalitis. Overtime she improved substantially. The opsoclonus, myoclonus, and ataxia di...
متن کاملInvestigating neuroblastoma in childhood opsoclonus-myoclonus syndrome.
OBJECTIVE Opsoclonus-myoclonus syndrome (OMS) is a serious, often disabling neurological illness of early childhood which is frequently associated with occult neuroblastoma. As investigation methods vary significantly, the authors assessed the usefulness of imaging and metabolic studies in tumour detection. METHODS Retrospective case note review of 101 OMS patients from two paediatric neurolo...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1987
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-1-7-8